Shhh! RNAi
Activity Description :
Students sequence cards featuring the steps of RNA interference (RNAi) — the mechanism used to silence gene expression and investigate its clinical applications.
ACTIVITY TYPE(S) : Worksheet, Discussion
DURATION : 45 minutes
SUBJECT AREAS : AP Biology and Biotechnology Pathways
KEY CONCEPTS : RNA interference (RNAi
LEARNING OBJECTIVES : Students will be able to describe the steps to RNA interference (RNAi) and its clinical applications.
BACKGROUND KNOWLEDGE NEEDED : Protein synthesis — The process by which cells create proteins, consisting of transcription (DNA to RNA) and translation (RNA to protein).
STANDARDS ALIGNMENT :
AP Biology Essential Knowledge 6.6.B.1: Gene regulation results in differential gene expression and influences cell products and functions.
AP Biology Essential Knowledge 6.6.B.2: Certain small RNA molecules have roles in regulating gene expression.
NOTE : This activity can be used alone or paired with Introns Out! and Splice of Life!
Activity Resources :
Video Reference :
Two ways to watch
This film is available in two versions: an 84-minute television cut, free to stream on PBS and the PBS App, and a 97-minute director's cut, available on Hoopla and Kanopy or by request from Uncommon Productions.
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